A density-matrix theoretical model to calculate
spectral line profiles of general multielectron ions in
plasmas is described. The line-profile calculation involves
electron collisional and radiative relaxation of ionic
states, the emitter's motion (Doppler effect) and its
interaction with a quasi-static ion microfield. Using the
LineDM computer package implementing this model, line-profile
calculations of the K- and L-shell transitions
in Al XII, Ar XVII, Ar XVI, Cu XX, and Xe XLV ions have been
performed in the context of plasma diagnostic issues of recent
laboratory experiments. Comparisons of the calculated line profiles
with experimental and other theoretical data show the applicability
of the model and package for the detailed computational analysis
of line radiation spectra from multielectron emitters in hot
dense plasmas.